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Collaboration in Biopharma: Harnessing the Power of Cloud-based Technologies

From banking to e-commerce, cloud computing has transformed the landscape of the world economy. It is also gradually changing the face of the biopharma industry. In the scientific world, effective communication and collaboration are essential to successful outcomes. Although biopharma has been slower than some other industries to adopt cloud-based technologies, the field is increasingly relying on the cloud to advance scientific knowledge.

Topic: Biobanking and Biorepository, Content: Post..........

The Evolution of Public Health Research: Malaria, Part 2

Malaria Elimination vs. Eradication, and Genetic Diversity vs. “Freezer Epidemiology”

It is because of its historic mission to eliminate malaria that the CDC is in Atlanta, Georgia. The agency is still deeply involved with the control of malaria, by providing technical assistance around the world, and continuing to protect the US population from the parasite. The CDC estimates that 1,500 people in the USA annually are infected with malaria while traveling, and the CDC tracks these cases and advises the medical community on accurate diagnosis and treatment.

Topic: Public Health Research, The Evolution of Pu..........

The Evolution of Public Health Research: Malaria, Part 1

Mosquitoes, the Military, and Why the CDC is in Atlanta

To most of us in the US, malaria is a health problem restricted to distant parts of the globe. Even in the international media, the disease receives little attention. However, it has only been since 1949 that Malaria was declared “eliminated” in the US.

Topic: Public Health Research, The Evolution of Pu..........

The Evolution of Public Health Research: Heart Disease, Part 2

Smoking, Salt and the Downside of Success

In the past 55 years, death rates from cardiovascular disease have declined by 68 percent—a two thirds reduction in mortality. Over the same period of time, death from stroke has declined by more than three fourths.

Topic: Public Health Research, The Evolution of Pu..........

The Evolution of Public Health Research: Heart Disease, Part 1

How a Radio Game Show and a Town in Massachusetts Invented Biobanking and Redefined Public Health Research

Topic: Public Health Research, The Evolution of Pu..........

Factors Affecting Participation Rates in Population-Based Biobanking

A systematic review and meta-analysis of baseline participation rates and their determinants performed by van Zon et al. (2016) found that recruitment methods and design affect participation rates.1 Population-based biobanks are essential platforms for innovation and knowledge generation in health care research, specifically in regards to how we prevent, treat and cure widespread diseases. Therefore, willingness to participate from the population is pivotal if biobank studies are to continue to contribute to public health research.

Topic: Biobanking and Biorepository, Topic: Public..........

Flawed Study Design—the Other “Pre-Analytical Variable” in Biomarker Research

Why are we failing to find biomarkers for early detection of disease?  Throughout our blog we write a great deal about biospecimen integrity and emphasize the control of pre-analytical variability in biospecimens. However, the highest quality biospecimens are wasted in the search for biomarkers if the study design is flawed. And the literature on biomarker discovery studies is filled with examples of poor study design, creating an overabundance of false positives that cannot be validated.

Topic: Biobanking and Biorepository, Topic: Labora..........

Pooling Biospecimen Collections into “Synthetic” Cohorts to Promote Personalized Medicine

Large longitudinal studies have become impractical on many levels. At well over $100 per patient enrolled, the traditional large cohort study has become cost-prohibitive. Nor is cost the only factor: another is time. By their very nature, cohort studies can take decades to yield benefits, both at the individual as well as the population level.1 However, these studies are still needed both for public health research and to support the implementation of personalized medicine.

Topic: Biobanking and Biorepository, Topic: Public..........