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Top Considerations When Establishing a Biospecimen Collection: Part II

In my previous post, I identified some items to consider when establishing a biospecimen collection, including the importance of printing information on a vial label and avoiding replication of specimen IDs when possible. In the second part of this blog series, I will discuss ways to ensure that critical data is easily captured and the integrity of your biospecimen collection is maintained.

Topic: Biobanking and Biorepository, Topic: Clinic..........

Top Considerations When Establishing a Biospecimen Collection: Part I

There are many logistical and operational considerations to take into account when setting up a clinical trial, longitudinal study, in vivo animal study, or any other study approach that will involve the collection of biospecimensThis two-part blog series will focus on helping you simplify your specimen management issues and keep sample-related costs low, from the perspective of the biorepository staff. Consider it a “lessons learned” from previous experiences…

Topic: Biobanking and Biorepository, Topic: Clinic..........

Controlling Sample Exposure to Temperature Variability


Maintaining the appropriate storage temperature of a clinical specimen/drug vial is critical for the downstream use of that sample. However, during their life cycle specimens are handled far more often than one probably realizes, and each handling event presents the opportunity for a temperature shift that may compromise the integrity of the sample for downstream research. Multiple and/or rapid temperature fluctuations can generate changes in enzymatic and other molecular activity that can result in loss of efficacy and potency or effect diagnostic results.

When considering temperature management, most people think about it in terms of the bigger picture. That means focusing on the storage unit:  is it monitored, is there a back-up generator, is a technician on call, and so forth. This makes sense, as a specimen can spend years in a freezer without being disturbed. Given that an ultralow (-80°C) freezer can hold more than 50,000 specimens, failure of a single unit can be catastrophic to a collection.

Topic: Biobanking and Biorepository, Content: Blog

National Children's Study Shows Why Biobanking Automation Pays Off

National Children's Study

Topic: Biobanking and Biorepository, Content: Post..........