bg-img9.jpg
8.jpg
The Growing Public Health Concern Surrounding Zika

Over the past several weeks, the Zika virus has morphed from an obscure disease into an international public health emergency, gaining global attention. This has left the public health research community with many questions; Where did the disease originate? How is it transmitted? How do we work together to develop and distribute a vaccine?

In this blog we'll explore the existing information surrounding the Zika virus and some of the challenges associated with vaccine development.

Topic: Biobanking and Biorepository, Topic: Cold-C..........

What You Need to Know About The Biomarkers Consortium

Established in 2006, The Biomarkers Consortium (BC) is a public-private partnership whose mission is to identify, develop and seek regulatory approval for new biological markers (biomarkers) to accelerate the detection, diagnosis and treatment of many diseases. These biomarkers support the development of new preventative medical measures, medical diagnostics and drug development.

Topic: Biobanking and Biorepository, Topic: Clinic..........

Researchers Propose a Validated Phenotyping Algorithm for Genetic Association Studies in Age-related Macular Degeneration

Age-related macular degeneration (AMD) is a leading cause of vision loss among people aged 50 and older. This multifactorial neurodegenerative disease damages the macula, responsible for sharp central vision. Rapid advancement of DNA sequencing technologies has allowed researchers to identify many AMD-associated genetic polymorphisms. However, phenotyping and patient recruitment are currently the most time-consuming steps facing researchers performing this work. Patient identification and DNA collection are often the rate-limiting steps in genetic association studies.

Facilitated by the rapid growth of electronic medical record (EMR)-linked DNA biorepositories, patient selection algorithms can improve efficiency in genetic association studies.

In this blog, we'll discuss a new study, published in Nature, where researchers show that using stepwise validation of such an algorithm could provide reliable cohort selection outcomes and, when networked with an EMR-linked DNA biorepository, replicate previously published AMD-associated single nucleotide polymorphisms (SNPs).

Topic: Biobanking and Biorepository, Topic: Clinic..........

Minimizing Your Sample Freeze/Thaw Cycle to Maintain Sample Integrity

Laboratory_Processing_Digram_to_Aliquot_or_NotIn designing clinical studies, much thought is given to controlling for clinical and demographic variability. For example, a well-designed study will carefully enroll patients of a particular disease type, stage, and treatment regimen. In addition, for each of these variables there will be determinations made as to how many patients of what age, sex, and ethnicity should be included in each of the clinical groups. By carefully considering the sample size needed for each variable, clinicians target specific and meaningful data when analyzing the results.

Topic: Laboratory Processing, Content: Blog