The Effect of Pre-analytical Variables on Plasma Samples Stored in Biobanks

Differences detected in respective biospecimen collections are more dependent on pre-analytical variables than on the inherent differences among the samples. Therefore, there is a parallel emphasis on standard protocol for biological sample collection and storage and identifying specific biomarkers as quality controls to assess the effects of pre-analytical factors on variability in the results. Mateos et al. (2016) used different, complementary proteomic techniques in separate, coordinated laboratories to search for quality biomarkers that would allow assessment of integrity and purity of plasma samples stored in biobanks.1

Topic: Biobanking and Biorepository, Topic: Labora..........