bg-img9.jpg

Top Five Most Popular Blogs of 2018

Posted by Katie Coyne on Dec 27, 2018 11:00:00 AM

Top52018 has been a year filled with new discoveries in the health and medical R&D space. Through our blog, we have shared great stories of our customers' work and discussed a wide-breadth of topics, focusing on advanced therapies, biological material, and public health research.

In case you missed some of the content we published over the past year, we've created a Top Five list of our most popular blogs of 2018. Take a look!

5. Long term biobanking: How long can you hold samples?

In order to prevent a loss of integrity among samples, all parties involved in the collection and storage of biospecimens must follow certain practices. For best results, these procedures should be based on up-to-date, relevant research studies that demonstrate the most effective methods for storing specimens, as well as the maximum length of time they can be stored safely. So what does our current research say? Read more...

4. Validation or Qualification - What's the Difference? 

For those studying, manufacturing, or experimenting with delicate pharmaceuticals and biological samples, the importance of sample storage and accurate temperature monitoring is well known. From a qualification and validation perspective, the equipment and processes used for shipping, storing (whether refrigerated storage or ultra cold storage), and other services must comply with the products’ requirements throughout the chain of custody.  The terms validation and qualification are used interchangeably and loosely at times. In this blog, we’ll take a look at the true difference between the two, and why they are both important components in managing your valuable biological material. Read more...

3. Why GMP? An Explanantion of Good Manufacturing Practice

GMP refers to the Good Manufacturing Practice Regulations published by the FDA under the Federal Food, Drug, and Cosmetic Act. As a response to concerns about substandard drug manufacturing practices occurring at the time, Congress enacted the 1962 Drug Amendments. These amendments instructed the FDA to require all drugs to be made according to Good Manufacturing Practice (GMP) as defined under FDA 21 CFR Part 210-211. Read more...

2. Whole Blood Basics: How to Maintain a Stable Sample

Like any other fluid or tissue sample, whole blood can be most effectively analyzed when its integrity is maintained throughout collection, processing and storage. But how do you maintain the quality of a whole blood sample when considering long term storage? What happens when a sample is not handled properly? Read more...

1. Avoiding Hemolysis in Blood Sample Collection and Processing

Depending on your point of view, red blood cells, or erythrocytes, are throwaways and a nuisance, ruining a good blood specimen if the cells burst and contaminate the sample. On the other hand, erythrocytes have significant value in specific types of research, and if your objective is biobanking these cells in an intact state, then hemolysis and the need for a re-draw is equally as much to be avoided. Erythrocyte cell membranes rupture easily, releasing hemoglobin and flooding the sample with potassium and other internal components. Fortunately, breakage of erythrocytes is easy to detect, as the hemoglobin turns the serum or plasma sample from pink to red, depending on the number of cells that have lysed. Hemolysis is a primary driver of the need for re-draw, resulting in wasted time and resources. How can hemolysis be prevented? Read more...

We hope you enjoyed this recap and want to thank you for being a part of our blog community. Stay tuned for fresh, new content in 2019!