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Shooting for the Moon: A New Cancer Immunotherapy Initiative

In 1962, President John F. Kennedy electrified the nation when he declared our intent to send a man to the moon. This year, President Obama declared a new “shoot for the moon” endeavor: to find an effective immunotherapy treatment for cancer by the year 2020.

Topic: Cell Therapy Solutions, Content: Blog

Expansion Cohort Clinical Trials and Your Cryogenic Supply Chain

One advantage to the traditional phase 1, 2, and 3 format of clinical trials is that it allows reasonable forecasting with regard to the clinical supply chain. This phase 1-2-3 format is rapidly changing, however, especially with regard to biological therapies, as more and more clinical trials include expansion cohorts. If you are planning clinical trials for a cell-based therapy that must be maintained in liquid nitrogen, and may potentially take the expansion cohort route, you should consider the impact on your distribution capabilities as soon as possible.

Topic: Cold-Chain Logistics, Topic: Cell Therapy S..........

Gut Bacteria Rivals Immunotherapies in Cancer Treatment

The human gut contains more than 100 trillion bacteria from perhaps 500 or more different species. In fact, gut bacteria outnumber the cells in the human body. The vast number of these bacteria has caused researchers to take a closer look at how they are related to health and disease. Now, breaking scientific research suggests that gut bacteria may be more important than anyone previously realized: they appear to be effective cancer treatments.

Topic: Laboratory Processing, Topic: Cell Therapy ..........

The Link Between Epigenetics and CRISPR-Cas9

When it was first released in 2012, the CRISPR-Cas system stunned scientists with its potential for revolutionizing biological research. Researchers initially noticed that bacterial genomes often contain “clustered regularly interspaced short palindromic repeats,” now dubbed CRISPR sequences. When scientists provide the Cas enzyme with a guide RNA sequence, they can tell it precisely where to slice the DNA. This allows unprecedented control over DNA slicing and insertion of new genetic code.

Topic: Laboratory Processing, Topic: Cell Therapy ..........

Increasing Global Cell Therapy Awareness: ISCT 2016

We are pleased to announce our participation as a platinum sponsor at next week's International Society for Cellular Therapy (ISCT) 22nd Annual Meeting in Singapore. This will be the first time that the ISCT Annual Meeting will be held in Asia and is a reflection of the increasing global awareness of the importance of Asia in the field of Cellular Therapies. With over 1000 international delegates registered to attend, ISCT 2016 is a great opportunity to network with experts within the global cell therapy arena. We are honored to showcase our global integrated solution for cell therapy clinical and commercial development in conjunction with our parent company, Thermo Fisher Scientific.

Topic: Cell Therapy Solutions, Content: Blog

Amazing Samples: Buccal Up for Some Cheeky Research

Most researchers know about buccal cells  the easily sloughed-off cells from the inside of the cheek. The collection of these cells is relatively non-invasive, which gives it many of the same advantages as spit and mucus that we’ve already discussed. Because of this, many studies, including some in social science, utilize buccal swabs to increase the amount of data they’re collecting.

However, even if it’s popular, don’t let that diminish its value. From biomarker studies to stem cell research, buccal cells have proven time and time again to be a hugely useful source of biological data. Last time in our Amazing Samples blog series, we scratched the surface of research with skin cells. This time, buccal up and get ready for a cheekier kind of Amazing Sample!

Topic: Biobanking and Biorepository, Topic: Cell T..........

World Stem Cells & Regenerative Medicine Congress


We are pleased to announce our participation at the 11th Annual World Stem Cells & Regenerative Medicine Congress on May 18-20 in London, England. In the past, this event focused on developments in stem cell therapies and innovations within regenerative medicine. As the industry progresses, this year's conference will focus on the cell therapies that have made it to market, the innovations of academia and universities, and the use of stem cells for drug discovery. Additionally, this year's event will be co-located with World Precision Medicine Congress and the Cord Blood World Europe.

Topic: Biobanking and Biorepository, Topic: Cell T..........

Breakthroughs & Setbacks in Cancer Immunotherapies

When President Nixon declared a war on cancer in 1971, scientists and the general public were energized about the possibility of eliminating these costly and deadly diseases. In the decades following, however, many initially promising treatments failed to deliver expected results. Although the medical community has become more skilled at targeting treatments to specific cancers, cancer remains the second most common cause of death in the United States.

Now, breakthroughs in immunological technology have renewed scientists’ enthusiasm and excitement about novel cancer treatments. Cancer immunotherapies have the potential to shift the medical landscape by reducing the toll the disease takes on patients and society at large.

Topic: Cell Therapy Solutions

Exploring Immunotherapies to Treat Crohn's Disease

Crohn’s disease and ulcerative colitis affect more than 1.6 million Americans, according to the Crohn’s and Colitis Foundation of America. Unfortunately, patients with Crohn’s disease are left with limited treatment options and no cure for the condition. This could change with new research supporting the use of immunotherapies to treat Crohn’s disease.

Topic: Cell Therapy Solutions, Content: Blog

Amazing Samples: Skin

Despite being the largest in the human body it’s easy to forget about skin as an organ, unless your research or practice directly involves it. It’s what we use to interact with the world and present ourselves. No one else, other than doctors, will really start thinking about your spleen or pituitary gland when they look at you. But just as with any other cell type, there is great research being conducted around skin.

Topic: Cell Therapy Solutions, Topic: Amazing Samp..........

[Webinar] The Seven Keys to Safeguarding Your Cryopreserved Cells

Safeguarding your samples throughout the entire cryopreservation process can be tricky and even unproductive, thanks to protocols that unknowingly undermine your results. Understanding the seven keys to protect your cryopreserved cells – from selecting the right storage temperatures and proper cooling methods to avoiding common safety hazards when using liquid nitrogen – can equip any lab with the knowledge necessary to ensure sample safety and optimal cryopreservation results.

Thermo Fisher Scientific's on-demand webinar, The Seven Keys to Safeguarding Your Cryopreserved Cells, explores the many variables involved in planning for cryopreservation in your cell culture process. Let's explore these steps and unlock the critical information to ensure high cell viability. 

Topic: Laboratory Processing, Content: Webinar, To..........

The Shift to Immunosurveillance in Breast Cancer Treatment

As we've discussed previously on the blog, bio-pharmaceutical entities are scrambling to bring new immunotherapies to the clinic, particularly in the treatment of cancers. The US Food and Drug Administration (FDA) and other regulatory agencies worldwide have already approved several immunotherapies for the treatment of various tumors, including melanoma and non-small cell lung carcinoma (NSCLC). However, pre-clinical and clinical trials to assess the safety and efficacy of investigational immunotherapies for breast cancer have only recently begun.

Topic: Biobanking and Biorepository, Topic: Cell T..........