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ISBER 2018 Annual Meeting

Fisher BioServices is pleased to announce our participation at the International Society for Biological and Environmental Repositories (ISBER) 2018 Annual Meeting in Dallas, TX on May 20-24. This year's theme will focus on seizing big opportunities in biobanking through data, collaboration and innovation.  ISBER 2018 is the premier global event in the field of biorepository and biospecimen management and we are honored to showcase our services and products in conjunction with our parent company, Thermo Fisher Scientific at booth #209. 

Topic: Biobanking and Biorepository, Content: Blog..........

The Golden Retriever Lifetime Study: 5 Year of Progress in Veterinary Health and Biobanking

Five years ago Fisher Clinical Services, a part of Thermo Fisher Scientific, embarked on a partnership with the Morris Animal Foundation to take veterinary research to a new level.  Since cancer is the leading cause of death in dogs over the age of two and golden retrievers (GRs) are at high risk of cancer development, Fisher Clinical Services is supporting the Foundation’s efforts in working to define the incidence and risk factors for cancer in man’s best friend.

Topic: Biobanking and Biorepository, Content: Blog..........

Supporting the Precision Medicine Initiative: The All of Us Research Program

In 2015, President Obama announced the Precision Medicine Initiative, a new effort to revolutionize health and disease treatment.1 Two key components of this initiative are:

Topic: Laboratory Processing, Topic: Biobanking an..........

Fisher BioServices Top Five Most Popular Blogs of 2017

2017 has been a year filled with new discoveries in the health and medical R&D space. Through our blog, we have shared great stories of our customers' work and discussed a wide-breadth of topics, focusing on advanced therapies, biological material, and public health research.

Content: Blog, Topic: Biobanking and Biorepository..........

Distributed Biobanking: An End to End Solution for FFPE Tissue Block Management

The process of formalin-fixed paraffin-embedding (FFPE) emerged in the late 19th century as a valuable histological method for stabilizing and preserving the morphology and cellular details of tissue samples. Additional advantages of preserving  tissues using the FFPE technique included long term room temperature storage without fear of degradation, and if tissues were correctly preserved, FFPE blocks could be used over decades to prepare additional slides for microscopic analysis (as long as there was remaining tissue in the paraffin block) with little or no tissue degradation. Significant advances in protein and nucleic acid isolation techniques from FFPE tissues have resulted in the generation of sufficient amounts of nucleic acid which can be used in a wide range of analytical techniques for the determination of structure and function of these key biological molecules.

Topic: Laboratory Processing, Topic: Biobanking an..........

The Effect of Pre-analytical Variables on Plasma Samples Stored in Biobanks

Differences detected in respective biospecimen collections are more dependent on pre-analytical variables than on the inherent differences among the samples. Therefore, there is a parallel emphasis on standard protocol for biological sample collection and storage and identifying specific biomarkers as quality controls to assess the effects of pre-analytical factors on variability in the results. Mateos et al. (2016) used different, complementary proteomic techniques in separate, coordinated laboratories to search for quality biomarkers that would allow assessment of integrity and purity of plasma samples stored in biobanks.1

Topic: Biobanking and Biorepository, Topic: Labora..........

Next-Gen Bioinformatics: The Expanding Role of Deep-Learning Algorithms

Deep-learning algorithms have shown significant promise as applications in natural language understanding, decision making, and speech and image recognition. These algorithms are now being applied in bioinformatics applications within the biopharma industry to manage the increasing amounts of data from high-throughput techniques. As a bioinformaticist, I am particularly fascinated with recent applications of these algorithms to predict a variety of biological processes and interactions, particularly with respect to proteins. 

Content: Blog, Topic: Public Health Research, Topi..........

Minimizing Waste through Practical Process Improvement

Personal Protective Equipment (PPE) is necessary to ensure the safety of personnel in a biopharma environment.  However, have you ever considered the amount of waste that accumulates from the use of laboratory nitrile gloves and other single use apparel?

Topic: Biobanking and Biorepository, Topic: Labora..........

Keeping It Cool: Protecting Cryopreserved Biological Samples from Degradation

As discussed on the Inside Biobanking blog, cryopreservation requires a slow cooling process to reach temperatures at or near the temperature of liquid nitrogen (−196°C). This method is standard practice in preserving biological samples. In their recent review, Woods et al. (2016) examined cryobiology applications in cryopreservation to identify new solutions to integrate into mainstream cell therapy.1

Topic: Cell Therapy Solutions, Content: Blog, Topi..........

Some Steps Toward Fit-For-Purpose, Future-Proof Specimens

We spill a good bit of virtual ink in our blogs and eBooks discussing biospecimen integrity, but the emerging term that is being used more and more often, is “fit–for-purpose.” Identifying a sample as fit-for-purpose implies molecular integrity, but goes beyond this to encompass all the variables that make a biological sample useful for research. Sample integrity focuses on the quality of individual samples, while the term fit-for-purpose can be interpreted as addressing entire collections.

Topic: Biobanking and Biorepository, Topic: Labora..........

Flawed Study Design—the Other “Pre-Analytical Variable” in Biomarker Research

Why are we failing to find biomarkers for early detection of disease?  Throughout our blog we write a great deal about biospecimen integrity and emphasize the control of pre-analytical variability in biospecimens. However, the highest quality biospecimens are wasted in the search for biomarkers if the study design is flawed. And the literature on biomarker discovery studies is filled with examples of poor study design, creating an overabundance of false positives that cannot be validated.

Topic: Public Health Research, Topic: Biobanking a..........

Gut Bacteria Rivals Immunotherapies in Cancer Treatment

The human gut contains more than 100 trillion bacteria from perhaps 500 or more different species. In fact, gut bacteria outnumber the cells in the human body. The vast number of these bacteria has caused researchers to take a closer look at how they are related to health and disease. Now, breaking scientific research suggests that gut bacteria may be more important than anyone previously realized: they appear to be effective cancer treatments.

Topic: Cell Therapy Solutions, Content: Blog, Topi..........