Minimizing Your Sample Freeze/Thaw Cycle to Maintain Sample Integrity

Laboratory_Processing_Digram_to_Aliquot_or_NotIn designing clinical studies, much thought is given to controlling for clinical and demographic variability. For example, a well-designed study will carefully enroll patients of a particular disease type, stage, and treatment regimen. In addition, for each of these variables there will be determinations made as to how many patients of what age, sex, and ethnicity should be included in each of the clinical groups. By carefully considering the sample size needed for each variable, clinicians target specific and meaningful data when analyzing the results.

Topic: Laboratory Processing, Content: Blog

[Video] The Journey of a Sample... in the Biobank Laboratory

So much depends on the subtle variations in biospecimens: these variations, when analyzed via genomics, proteomics, metabolomics, and similar studies, are the foundation of both disease-based and drug-based biomarker discovery. And if the unique "-omics" of a sample is to yield results that lead to improvements in medical research and healthcare, such as understanding disease cause/progression (predictive/prognostic biomarker) to PK/PD in clinical trials (surrogate endpoints), then the entire integrity of the specimen must be protected, or biomarker research/study can go astray. 

Content: Video, Topic: Laboratory Processing

National Children's Study Shows Why Biobanking Automation Pays Off

National Children's Study

Topic: Biobanking and Biorepository, Content: Post..........

Got Enough DNA?

With funding the way it is today, long gone is the era of producing unlimited DNA from study participants' cell lines.  Many study coordinators are faced with the challenge of how to manage the limited amount of DNA collected from participants during a clinical trial.  Through years of working with many clients involved in clinical trials and cohort studies, I've summarized some of the important considerations that can help you manage this invaluable resource. 

Topic: Laboratory Processing, Content: Blog

Free Webinar - Laboratory Processing, Automation, and Analysis for Biobank Samples and Clinical Biospecimens

Biobanks and clinical translational research centers play a critical role in the research information network, and often requires a LIMS (Laboratory Information Managmenet System) integrated workflow from sample receipt through processing, analysis, and storage/preservation. Today, many labs are facing bottlenecks in their workflow. Michael Blackburn, a senior research investigator at Sanofi-Aventis, commented about lab bottlenecks in a recent article "Improving Workflows In An Analytical Laboratory", "Analytical labs face a number of bottlenecks, depending of course on what they are analyzing and whether or not they are in a regulated environment".

Topic: Laboratory Processing, Content: Webinar