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World Immunization Week

Beginning in 2012, The World Health Organization (WHO) designated the last week of April as “World Immunization Week”.  This year, World Immunization Week will take place April 24th-30th with the theme “Protected Together, #Vaccines Work”.[i]

Topic: Public Health Research, Topic: Clinical Tri..........

Receiving Finished Pharmaceuticals at the Repository

The value of your work lies in the integrity of your materials. Ensuring pharmaceutical agents are handled properly and maintained at the correct temperature throughout all processes is imperative to maximal long term viability and usability. This means not only during the processing and preparation of finished pharmaceuticals for storage—it also means during the transportation process

Content: Poster, Topic: Public Health Research, To..........

Supporting the Precision Medicine Initiative: The All of Us Research Program

In 2015, President Obama announced the Precision Medicine Initiative, a new effort to revolutionize health and disease treatment.1 Two key components of this initiative are:

Topic: Laboratory Processing, Topic: Biobanking an..........

Thinking Outside of the Freezer: DNA and RNA Storage

While ultra-low temperatures are the current state-of-the-art solution for biospecimen storage, ambient storage is an interesting option and could be superior in certain limited situations. For many types of samples it’s possible that we will always have to use ultra-low temperatures for long-term storage. For other sample types, such as DNA and RNA, there are alternative solutions.  

Topic: Biobanking and Biorepository, Content: Blog..........

Fisher BioServices Top Five Most Popular Blogs of 2017

2017 has been a year filled with new discoveries in the health and medical R&D space. Through our blog, we have shared great stories of our customers' work and discussed a wide-breadth of topics, focusing on advanced therapies, biological material, and public health research.

Content: Blog, Topic: Biobanking and Biorepository..........

World AIDS Day 2017

December 1st is World AIDS Day. Each year, this day is an opportunity to raise awareness of the AIDS pandemic, unite in the fight against HIV, and remember those lost to an AIDS-related illness. The 2017 World AIDS Day theme is “Increasing Impact through Transparency, Accountability, and Partnerships”. This theme reflects a shift in attitude from crisis toward control, and the role of partnerships in reaching our collective goals.

Topic: Biobanking and Biorepository, Content: Blog..........

Transitioning to a New Biobank Model at a Time of Change: An AstraZeneca & Fisher BioServices Perspective

The AstraZeneca (AZ) UK Biobank offers long-term storage of, and rapid access to, ~1 million human biological samples (HBS) from AZ Oncology clinical trials, collaborators and commercial sources. A variety of sample types are managed including normal tissue, tumor tissue, blood/plasma/serum, urine and other excreta, FFPE blocks, glass slides and genetic samples (DNA/blood).

Topic: Biobanking and Biorepository, Content: Post..........

Distributed Biobanking: An End to End Solution for FFPE Tissue Block Management

The process of formalin-fixed paraffin-embedding (FFPE) emerged in the late 19th century as a valuable histological method for stabilizing and preserving the morphology and cellular details of tissue samples. Additional advantages of preserving  tissues using the FFPE technique included long term room temperature storage without fear of degradation, and if tissues were correctly preserved, FFPE blocks could be used over decades to prepare additional slides for microscopic analysis (as long as there was remaining tissue in the paraffin block) with little or no tissue degradation. Significant advances in protein and nucleic acid isolation techniques from FFPE tissues have resulted in the generation of sufficient amounts of nucleic acid which can be used in a wide range of analytical techniques for the determination of structure and function of these key biological molecules.

Topic: Laboratory Processing, Topic: Biobanking an..........

The Effect of Pre-analytical Variables on Plasma Samples Stored in Biobanks

Differences detected in respective biospecimen collections are more dependent on pre-analytical variables than on the inherent differences among the samples. Therefore, there is a parallel emphasis on standard protocol for biological sample collection and storage and identifying specific biomarkers as quality controls to assess the effects of pre-analytical factors on variability in the results. Mateos et al. (2016) used different, complementary proteomic techniques in separate, coordinated laboratories to search for quality biomarkers that would allow assessment of integrity and purity of plasma samples stored in biobanks.1

Topic: Biobanking and Biorepository, Topic: Labora..........

Halting the Next Ebola Epidemic

Prior to 2014 Ebola was mostly seen as a deadly disease, but contained in remote areas of the world with a low likelihood of spreading. However, this false impression was dispelled when the disease hit heavily populated urban areas. Suddenly the world realized the Ebola outbreaks could reach epidemic proportions, and with an average fatality rate of approximately 50%, the potential impact could be catastrophic. In response, the scientific community rushed to develop a vaccine.

Topic: Biobanking and Biorepository, Topic: Public..........

Use of Mobile Technology to Enhance Biospecimen Quality and Biobank Efficiency

Population-based biobanking is an essential aspect of biomedical research. When biobank samples are collected outside of clinical or research facilities, chances for variation in sample collection, handling, and shipping increase. Any lack of standardization before, during, or after collections can generate unwanted pre-analytical variability that hurts future use of biospecimens.

Topic: Biobanking and Biorepository, Topic: Public..........

Next-Gen Bioinformatics: The Expanding Role of Deep-Learning Algorithms

Deep-learning algorithms have shown significant promise as applications in natural language understanding, decision making, and speech and image recognition. These algorithms are now being applied in bioinformatics applications within the biopharma industry to manage the increasing amounts of data from high-throughput techniques. As a bioinformaticist, I am particularly fascinated with recent applications of these algorithms to predict a variety of biological processes and interactions, particularly with respect to proteins. 

Content: Blog, Topic: Public Health Research, Topi..........